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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UHRF1 All Species: 22.73
Human Site: S165 Identified Species: 50
UniProt: Q96T88 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T88 NP_001041666.1 793 89814 S165 R V T R K A P S R D E P C S S
Chimpanzee Pan troglodytes XP_001139655 792 89650 S165 R V T R K A P S R D E P C S S
Rhesus Macaque Macaca mulatta XP_001082893 795 89906 S165 R V T R K A P S R D E P C S S
Dog Lupus familis XP_868468 799 89797 S168 R V T R K A P S Q D E P C S S
Cat Felis silvestris
Mouse Mus musculus Q8VDF2 782 88285 S161 Q V Q K R A L S E D E P C S S
Rat Rattus norvegicus Q7TPK1 774 87430 S161 Q V Q K K A L S E E E P C S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507628 851 95788 L229 S R E N T N N L D S A P S T S
Chicken Gallus gallus XP_418269 760 84868 T158 C A V A D Q Q T T I P E E D V
Frog Xenopus laevis NP_001129236 772 86955 P161 N V S K K V G P Y G T L P E V
Zebra Danio Brachydanio rerio NP_998242 775 87072 P165 I V K V T K T P A E D G G P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791602 653 73619 T73 S I R P R A R T M I D Y E D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.2 88.1 N.A. 74.9 75.7 N.A. 53.3 71.5 66.5 68 N.A. N.A. N.A. N.A. 47.5
Protein Similarity: 100 99.7 98.8 92.7 N.A. 87 87.5 N.A. 68.5 82 79.9 83 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 100 100 93.3 N.A. 60 60 N.A. 13.3 0 13.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 80 N.A. 20 6.6 26.6 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 64 0 0 10 0 10 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 55 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 10 46 19 0 0 19 0 % D
% Glu: 0 0 10 0 0 0 0 0 19 19 55 10 19 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 10 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 19 0 0 0 0 0 % I
% Lys: 0 0 10 28 55 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 19 10 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 10 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 37 19 0 0 10 64 10 10 0 % P
% Gln: 19 0 19 0 0 10 10 0 10 0 0 0 0 0 0 % Q
% Arg: 37 10 10 37 19 0 10 0 28 0 0 0 0 0 0 % R
% Ser: 19 0 10 0 0 0 0 55 0 10 0 0 10 55 64 % S
% Thr: 0 0 37 0 19 0 10 19 10 0 10 0 0 10 0 % T
% Val: 0 73 10 10 0 10 0 0 0 0 0 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _